Every breakthrough in science begins with doubt.

In fact, we would argue that without doubt there cannot be a significant innovation in thought.

When Galileo said the Earth revolved around the sun, he was condemned.
When doctors first resisted washing their hands, they thought it was unnecessary.
When scientists said bacteria, not stress, caused ulcers, they were ridiculed.

First it is doubted, then it is debated, then it hard to imagine a time it wasn’t believed.

We believed that the Skin- Brain connection could be tapped into to improve both skin and mood. It is well known that the skin has millions of free nerve endings, that the skin and brain developed embryologically at the same time and that many of the same neuropeptides in our brain also exists in our skin. There is a well -established subconscious communication highway between our skin and brain that helps us to navigate and interpret our environment. It is why you feel good when sitting in the sun or feel more empathetic when drinking a warm coffee, pull you finger off an oven before you consciously even recognize the pain. And. most importantly, our skin brain connections lays the infrastructure that allows us a jolt of feel good and happy when caressing or hugging a loved one.  We were just surprised nobody yet had explored this obvious connection for skin care.  The theoretical science was sitting right there in front of all our eyes! 

So we jumped on the idea and spent years developing a formulation that would leverage the Skin-Brain connection, and once we thought we had the ideal recipe, we had to prove it –  but for ourselves first. We would not say anything or put our names on it unless we could stand behind the science.

So, when we say skincare can influence not just your skin, but also your mood, confidence, and relationships, many bat an eye. And we get it! we did too until we put it to the test.

Tested. Proven. Published.

I wasn’t just any simple test. We put it through the most rigorous of clinical testing  – the gold standard for proving efficacy, a double-blinded, placebo-controlled crossover trial. In this design, the subjects and the investigator don’t know what was used. It could be placebo or it could be XOMD. The products come in white, unlabeled bottles that looked exactly the same! There is no way to game or cheat the system.

And when we got the results, we were astonished!

They weren’t just significant but highly statistically significant – well beyond what can be expected in a clinical trial for a cosmetic topical. The results were so extraordinary that we presented it at a medical conference and submitted it to a peer reviewed medical journal (Journal of Cosmetic Dermatology (2024)) and it was accepted, once again clearing a very high bar when it comes to scientific legitimacy.

What were some of the impressive results?

• Skin Quality: Significant improvements in radiance, smoothness, evenness, dewiness, redness, dryness, and photodamage after just 4 weeks.
• First Impressions: 239 blinded evaluators rated women using XOMD as more attractive, socially skilled, and successful—some even judged them as looking 3 years younger.
• Perception of Others: XOMD users found others more attractive 87.5% of the time (vs. 12.5% in the placebo group).
• Intimacy: 90% of sexual satisfaction metrics improved—something no standard moisturizer has ever promised.
• Confidence: 86% of women reported feeling more confident, more relaxed, and more magnetic after 8 weeks.
• But read it for yourself! results

Real Women, Real Words

Objective data is powerful. But the subjects in the trial also were interviewed and kept treatment diaries so we could capture their subjective feelings. And what did we find? Well, the results really started to come to life when you read below:

• “My friends noticed that I was more upbeat and super happy.” — Diana
• “Our relationship improved significantly, from zero to a ten.” — Priscila
• “It enhances not only appearance, but overall confidence level.” — Yvette
• “It works on not just a physical level, but an emotional level.” — Dilmara
• “I have been stopped by random strangers to tell me I am stunning and just glowing.” — Haley

So we started to believe that our theory of a neuro-cosmetic topical skin care that is inspired by the skin brain connection is feasible. We packaged it and launched it to the public in early 2025. And now so many women are discovering what skeptics said was impossible.

How It Works — The Biology Behind the Breakthrough

If you’re wondering how skincare can affect mood, the answer is simple: your skin is not just a barrier, it’s a communication organ.

• Your skin produces oxytocin (“the love hormone”), along with serotonin and dopamine.
• Skin is packed with oxytocin receptors that, when activated, reduce inflammation, speed repair, and improve elasticity.
• XOMD’s jasmine extract stimulates the same receptors as touch—triggering an oxytocin-like effect in the skin.

This explains why touch feels so healing—and why skincare designed to activate these pathways can change both how you look and how you feel.

XOMD products are inspired by, but do not contain, oxytocin. XOMD products are not intended to diagnose, treat, cure or prevent any disease. Consult your healthcare professional if you have any concerns or underlying conditions.

Three Ways to Overcome Skepticism

We know people need different kinds of proof. So, we’ve built them all into XOMD:

1. See the Social Proof — Women, from late 30s to 60s, are sharing stories of better skin and better confidence.
2. See the Science — A peer-reviewed, placebo-controlled study showed measurable results in skin, mood, confidence, and intimacy.
3. See for Yourself — Risk-Free — Our 4-week guarantee means if you don’t look and feel the difference, we’ll make it right. No leap of faith required.

From Skepticism to Self-Belief

Think about it:

• If I told you 15 years ago you could sit in a café in Chicago and video communicate through your phone with a friend in Istanbul instantly and have nothing plugged into the wall, you would say, “How? That makes no sense.” And if I told you there were all these waves called WiFi surrounding you that we can tap into them and send information seamlessly thousands of miles away you would think it impossible. Well now we can’t imagine life without it.

What once sounded far-fetched quickly became everyday reality.

XOMD may be the next breakthrough on that list: skincare that works not just on your skin, but on your confidence, your connection, and your life.

Still skeptical? Good. Every breakthrough starts there. Try XOMD risk-free for 4 weeks, and decide for yourself if the impossible is now undeniable.