Skin Anarchy: 2026 Science of Skin Award Winner

INTOXICATE Renewal Serum

Hormone-smart Serum

INTOXICATE Renewal Serum

Name: INTOXICATE Renewal Serum
Brand: XOMD
SKU: SER-2001
Price: 188.00 USD
Availability: InStock

$188.00

Our guarantee

Radiant skin in 4 weeks or your money back.

Description

INTOXICATE Renewal Serum

CORRECT

Unwanted Pigment • Redness • Inflammaging

For all skin types. Safe for sensitive, post-treatment and compromised skin. Especially relevant for skin experiencing age- and hormone-related changes.

Hormonal shifts, environmental stress and inflammation can show up on the skin as uneven pigmentation, visible redness and accelerated signs of aging.

INTOXICATE is a lightweight corrective serum formulated with OX Factor™ and targeted antioxidant, brightening and skin-calming ingredients to address these visible changes. It helps improve the appearance of unwanted pigment, calm visible redness and support a more even, luminous complexion.

Inflammaging is the root of all skin aging complaints. INTOXICATE takes a broad approach by addressing the visible effects of both pigment, irritation, and redness for skin that looks clearer, calmer and more resilient.

Benefits

100% of users reported brighter and more radiant skin
87% Users demonstrated smoother skin
83% of users had improved dewiness in their skin
100% of users made a better first impression

*When using the full XOMD skin regimen. Explore clinical trial results.

Key ingredients

Phyto OX Peptide Complex™: Proprietary botanical and peptide-based, hormone-smart skin technology

Beta Glucan: Helps soothe and hydrate stressed skin

Phospholipids: Skin-calming properties to protect cells and reduce redness and uneven skin tone

Fruit Extracts: Antioxidants for the skin. Brightens and boosts microcirculation to illuminate skin

Full ingredient list

Water (Aqua, Eau), Glycerin, Butylene Glycol, Propanediol, Pentylene Glycol, Coco-Caprylate/Caprate, Triheptanoin, Caprylic/Capric Triglyceride, Jasminum Grandiflorum (Jasmine) Flower Extract, Beta-Glucan, Palmitoyl Tripeptide-5, Evodia Rutaecarpa Fruit Extract, Trisodium Ethylenediamine Disuccinate, Phospholipids, Ceratonia Siliqua (Carob) Fruit Extract, Jasminum Officinale (Jasmine) Flower Extract, Caprylyl Glycol, C9-12 Alkane, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, 1,2-Hexanediol, Decyl Glucoside, Polyurethane-100, Phenethyl Alcohol, Sodium Hydroxide, Ethylhexylglycerin, Phenoxyethanol

Intentionally Clean

The formula

Beta Glucan

For deep hydration and barrier repair

The formula

OX Factor

Minimizes redness and hydrates

The formula

Evodia Fruit

Calms and brightens the skin

The formula

Palmitoyl Tripeptide-5

Stimulates collagen and firms

The formula

Phospholipids

For barrier repair and improved delivery of actives

Step 1

Twist

Twist top cap to open

Step 2

Dispense

Dispense two pumps onto your fingertip

Step 3

Dab

Gently dab onto your cheeks, chin, and forehead

Step 4

Massage

Massage evenly over your face, using the pads of your fingertips.

Step 5

Cap

Return the cap to the bottle

Hormone-smart Skincare

Powered by OX Factor™

Love. Trust. Intimacy. Women who experience them positively glow from the inside out. The reason? Oxytocin, the “love hormone.” XOMD with OX Factor features a revolutionary blend of phytopeptides and phospholipids inspired by the science and benefits of oxytocin.

Go Beyond Skin Deep

XOMD products are inspired by, but do not contain, oxytocin. XOMD products are not intended to diagnose, treat, cure or prevent any disease. Consult your healthcare professional if you have any concerns or underlying conditions.

Confidence

XOMD users felt more confident — after just 8 weeks of use

Radiance

XOMD users agreed skin looked brighter & more radiant — after just 4 weeks of use

Changes

XOMD users see a striking difference — after just 8 weeks of use

Intimacy

XOMD users report greater sexual satisfaction — in 18/20 categories tested after just 8 weeks of use

Recommended

86% would recommend XOMD to a friend — after just 8 weeks of use

Appearance

0Yrs

XOMD users on average looked 3 years younger than their real age — after just 8 weeks of use

Skin Tone

83% saw improved skin tone — after just 8 weeks of use

Attraction

XOMD users found the opposite gender more attractive — after just 8 weeks of use

For details about study design and results, please see our published study.

FAQs

Do XOMD products contain oxytocin?

While inspired by the science and benefits of oxytocin, XOMD products and patent-pending OX Factor do not contain oxytocin.

Can XOMD products be used to treat mood?

Our products are formulated for cosmetic use and are not intended to diagnose, treat, cure or prevent any disease. Consult your healthcare professional if you have any concerns or underlying conditions.

How clean are XOMD products?

XOMD products are designed to be intentionally clean. They are paraben, sulfate and fragrance free.

Do XOMD products contain parabens?

XOMD products do not contain parabens.

Do XOMD products contain sulfates?

XOMD products do not contain sulfates.

Do XOMD products contain fragrances?

No. This was a very intentional formulation decision. We chose not to add fragrance because we wanted the products to be as clean and skin friendly as possible, particularly for patients with sensitive skin or those using the products after aesthetic procedures.

Some users notice the slight, natural scent of the formulation itself rather than an added fragrance. Our commitment is to remain disciplined in our formulation philosophy and prioritizing clean, hormonally thoughtful skincare.

Do you test on animals?

XOMD does not conduct animal testing.

Are XOMD products safe for all skin types?

Yes. XOMD products are safe for all skin types.

What should I do if my skin has a reaction to XOMD products?

If you have a reaction to XOMD products, stop use immediately. Then please contact us at info@xomdskin.com to report your reaction.

What does it mean that XOMD products were rigorously tested in a double-blind, placebo-controlled study?

Double-blind, placebo-controlled clinical studies are one of the highest standards in clinical research. Placebo controlled means that XOMD products were tested and compared to products with the same vehicle, but not necessarily the same beneficial ingredients as the XOMD products. Double blind means that neither the study participants nor the physicians conducting the research knew whether the participants had XOMD products or placebo formulations. In many assessments, the results that study investigators and participants who received XOMD products observed were statistically significant – meaning they could not be explained by chance alone. Most cosmetics do not conduct this type of testing, because it is complex and expensive. We wanted to demonstrate to XOMD users that our products really work. So we put them up to the test and we were blown away by the results. We are confident that once you try XOMD, you’ll have the same reaction.

From our community

Customer reviews

the packaging is beautiful but the product seems to be irritating my skin and causing it to burn and feel very dry unfortunately

Improved skin texture and overall appearance

I love this skincare line! Using the cleanser, the serum, and the moisturizer twice a day has improved the texture and appearance of my skin in about 6-8 weeks. I no longer wear foundation or concealer even when dressing up for formal occasions. The serum and moisturizer absorb quickly and leave my skin glowing but never slick or shiny.

Mega Fan

I'm a long term patient of Dr. Fabi in San Diego. I've been using all the products since the beginning. Stop wasting money on drug store products that don't work. These products are for those spending money on their face, and know what the investment involves. Quality ingredients cost $$$. I'm very happy with the products....

PERFECT GLOW

It feels lightweight on the skin and absorbs quickly, leaving my face soft, hydrated, and glowing.

I’ve noticed a visible improvement in my skin’s texture and overall radiance. It’s definitely a must-have in my skincare routine!

It’s wonderful!

I’ve been using it for weeks, and every day I love the results of this serum even more 🫶🏻
I have rosacea-prone skin, and this serum calms my skin while also keeping it well hydrated. I must confess that after just a week of using it, I noticed the area around my eyes looked less puffy—my reaction was literally “wow, my face looks 15 again” 😆 (I’m 36 🤭).
I love the entire XOMD line, but if I had to choose a favorite, it would definitely be this little bomb of a youth elixir ✨!

“I typically have more red undertones. When I looked at the before and after photos, I noticed that the redness was gone, which is fabulous.”

Carissa

“Our sexual relationship has been really good – and he even noticed my skin.”

Diana

“My friends keep saying, ‘Your skin is so glowy. What have you been doing?’ And I tell them, 'It’s the serum!’”

Lexi

“Siento que estos productos no solamente trabajan en lo físico pero también trabajan por dentro, trabajan en la parte emocional.”

Dilmara

Mood

“My friends noticed that I was more upbeat and super happy.”

– Diana

Relationships

“Our relationship improved significantly, from zero to a ten.”

– Priscila

Skin

“My glow was my natural color.”

– Rhea

Mood

“It enhances not only appearance, but overall confidence level.”

– Yvette

Mood

“It works on not just a physical level, but an emotional level.”

– Dilmara

Individual results may vary. Study participants utilized products for 8 weeks.

Research & perspectives

Published research
International Expert Consensus on Integrated Skincare Active Ingredients for Pretreatment and Posttreatment Use With Medical Aesthetic Procedures to Enhance Skin Benefits
Peter Bjerring · Zoe D. Draelos · Sabrina G. Fabi · Greg J. Goodman · Kwun Cheun Hau · Ariel Haus · Izolda Heydenrych · Jihee Kim · Liang-Chen Lin · Karim Sayed · Hema Sundaram · Rieko Tsubouchi · Yan Wu · Patricia Brieva · Hina Choudhary · Leihong Flora Xiang
Published research
Intranasal Oxytocin and Physical Intimacy for Dermatological Wound Healing and Neuroendocrine Stress: A Randomized Clinical Trial
Ekaterina Schneider · Cristóbal Hernández · Robert Brock · Monika Eckstein · Guy Bodenmann · Markus Heinrichs · Ulrike Ehlert · Severin Läuchli · Beate Ditzen
Published research
Neo-Romanticism in Aesthetic Medicine
Steven H. Dayan
Published research
Neuroendocrine Pathways in Skin Health and Homeostasis: A Systematic Review
Elizabeth J. Kream · Rachel Shireen Golpanian · Anna-Marie Hosking · Monica Boen · Sabrina G. Fabi
Published research
Oxytocin and Women’s Health in Midlife
Galit Levi Dunietz · Lucas J. Tittle · Sunni L. Mumford · Louise M. O’Brien · Ana Baylin · Enrique F. Schisterman · Ronald D. Chervin · Larry J. Young
Published research
Oxytocin is expressed in epidermal keratinocytes and released upon stimulation with adenosine 5′-[γ-thio]triphosphate in vitro
Sumiko Denda · Kentaro Takei · Junichi Kumamoto · Makiko Goto · Moe Tsutsumi · Mitsuhiro Denda

Explore all published research

INTOXICATE Renewal Serum

Our guarantee

Radiant skin in 4 weeks or your money back.